Merck Animal Health Announces Availability of Circumvent® CL, a Ready-to-use Vaccine Protecting Pigs Against Porcine Circovirus Types 2a and 2d and Lawsonia intracellularis

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RAHWAY, N.J. – Merck Animal Health, known as MSD Animal Health  outside of the United States and Canada, a division of Merck & Co., Inc., Rahway, N.J., USA  (NYSE:MRK), today announced the commercial availability of CIRCUMVENT® CL vaccine, a  ready-to-use vaccine formulated to protect pigs three weeks of age and older against disease  caused by Porcine Circovirus (PCV) Types 2a and 2d and Lawsonia intracellularis

CIRCUMVENT CL is designed to simplify herd health programs by delivering dual  protection in a ready-to-use formulation that requires no mixing or reconstituting. This new  product complements Merck Animal Health’s existing swine portfolio, including CIRCUMVENT  CML, a single-dose, ready-to-use vaccine that protects against PCV Types 2a and 2d,  Mycoplasma hyopneumoniae (M. hyopneumoniae) and Lawsonia intracellularis in pigs three  weeks of age and older, which was introduced in 2023. CIRCUMVENT CL omits the  mycoplasma component to meet the needs of herds that are now M. hyopneumoniae-negative  while maintaining robust protection against PCV and Lawsonia intracellularis. 

“Merck Animal Health is committed to delivering innovative, practical solutions that help  veterinarians and producers protect herd health while streamlining on-farm operations,” said  Brett O’Brien, V.M.D., swine technical services, Merck Animal Health. “CIRCUMVENT CL  provides trusted protection against two of the most significant enteric and systemic disease  agents impacting swine production in a ready-to-use formulation. By offering options such as  CIRCUMVENT CML and CIRCUMVENT CL, we enable tailored vaccination strategies that  simplify vaccine handling and administration.” 

Key product benefits of CIRCUMVENT CL include:  

  • Dual protection: Effective against disease caused by Porcine Circovirus Types 2a  and 2d and Lawsonia intracellularis in pigs three weeks of age or older. 
  • Ready-to-use: Single-bottle presentation requires no mixing or reconstituting, helping  to reduce preparation time and potential handling errors. 
  • Flexible herd options: Designed for use in herds where M. hyopneumoniae vaccination is not required, providing a targeted solution for M .hyopneumoniae-negative operations.
  • Complementary portfolio: Adds to Merck Animal Health’s CIRCUMVENT family,  enabling veterinarians to choose the formulation that best fits herd health status and  management goals. 

CIRCUMVENT CL is available in 50- and 250-dose presentations. A 500-dose  presentation will be available in Q1 2026. For more information, contact your Merck Animal  Health sales or technical services representative or visit https://www.merck-animal-health usa.com/species/swine

About Merck Animal Health  

At Merck, known as MSD outside of the United States and Canada, we are unified  around our purpose: We use the power of leading-edge science to save and improve lives  around the world. For more than a century, we’ve been at the forefront of research, bringing  forward medicines, vaccines and innovative health solutions for the world’s most challenging  diseases. Merck Animal Health, a division of Merck & Co., Inc., Rahway, N.J., USA, is the global  animal health business of Merck. Through its commitment to The Science of Healthier Animals®, Merck Animal Health offers veterinarians, farmers, producers, pet owners and governments one  of the widest ranges of veterinary pharmaceuticals, vaccines and health management solutions  and services as well as an extensive suite of connected technology that includes identification,  traceability and monitoring products. Merck Animal Health is dedicated to preserving and improving the health, well-being and performance of animals and the people who care for them.  It invests extensively in dynamic and comprehensive R&D resources and a modern, global  supply chain. Merck Animal Health is present in more than 50 countries, while its products are  available in some 150 markets. For more information, visit www.merck-animal-health.com and  connect with us on LinkedIn, Facebook, X (formerly Twitter) and Instagram.  

Forward-Looking Statement of Merck & Co., Inc., Rahway, N.J., USA This news release of Merck & Co., Inc., Rahway, N.J., USA (the “company”) includes  “forward-looking statements” within the meaning of the safe harbor provisions of the U.S.  Private Securities Litigation Reform Act of 1995. These statements are based upon the current  beliefs and expectations of the company’s management and are subject to significant risks and  uncertainties. There can be no guarantees with respect to pipeline candidates that the  candidates will receive the necessary regulatory approvals or that they will prove to be  commercially successful. If underlying assumptions prove inaccurate or risks or uncertainties  materialize, actual results may differ materially from those set forth in the forward-looking  statements. 

Risks and uncertainties include but are not limited to, general industry conditions and  competition; general economic factors, including interest rate and currency exchange rate  fluctuations; the impact of pharmaceutical industry regulation and health care legislation in the  United States and internationally; global trends toward health care cost containment;  technological advances, new products and patents attained by competitors; challenges inherent  in new product development, including obtaining regulatory approval; the company’s ability to  accurately predict future market conditions; manufacturing difficulties or delays; financial  instability of international economies and sovereign risk; dependence on the effectiveness of the  company’s patents and other protections for innovative products; and the exposure to litigation,  including patent litigation, and/or regulatory actions. 

The company undertakes no obligation to publicly update any forward-looking statement,  whether as a result of new information, future events or otherwise. Additional factors that could  cause results to differ materially from those described in the forward-looking statements can be  found in the company’s Annual Report on Form 10-K for the year ended December 31, 2024 and the company’s other filings with the Securities and Exchange Commission (SEC) available  at the SEC’s Internet site (www.sec.gov). 

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